CYM50358


Catalog No. Size PriceQuantity
M30692-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

CYM50358 is a potent and selective S1PR4 antagonist, with an IC50 of 25 nM. CYM50358 can be used for the research of influenza infection.

Product information

CAS Number: 1314212-39-9

Molecular Weight: 389.28

Formula: C20H18Cl2N2O2

Chemical Name: N-[4-(aminomethyl)-2,6-dimethylphenyl]-5-(2,5-dichlorophenyl)furan-2-carboxamide

Smiles: CC1C=C(CN)C=C(C)C=1NC(=O)C1=CC=C(O1)C1=CC(Cl)=CC=C1Cl

InChiKey: QWJOPXDAQCDRRM-UHFFFAOYSA-N

InChi: InChI=1S/C20H18Cl2N2O2/c1-11-7-13(10-23)8-12(2)19(11)24-20(25)18-6-5-17(26-18)15-9-14(21)3-4-16(15)22/h3-9H,10,23H2,1-2H3,(H,24,25)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

CYM50358 shows less potent inhibition of S1PR1 (IC50=6.4 μM). CYM50358 (10 μM) has no effect on the collagen-induced HSP27 phosphorylation, markedly reverses the suppressive effect of S1P on the collagen-induced phosphorylation of HSP27.

Products are for research use only. Not for human use.

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