Description
Autogramin-2 potently inhibits autophagy induced by either starvation (IC50=0.27 μM) or mTORC1 inhibition (Rapamycin; IC50=0.14 μM).
Product information
CAS Number: 2375541-45-8
Molecular Weight: 417.52
Formula: C21H27N3O4S
Chemical Name: tert-butyl 2-[4-(propan-2-yloxy)benzamido]-4H,5H,6H,7H-[1,3]thiazolo[5,4-c]pyridine-5-carboxylate
Smiles: CC(C)OC1C=CC(=CC=1)C(=O)NC1=NC2CCN(CC=2S1)C(=O)OC(C)(C)C
InChiKey: PNSFNXURLSDVRV-UHFFFAOYSA-N
InChi: InChI=1S/C21H27N3O4S/c1-13(2)27-15-8-6-14(7-9-15)18(25)23-19-22-16-10-11-24(12-17(16)29-19)20(26)28-21(3,4)5/h6-9,13H,10-12H2,1-5H3,(H,22,23,25)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 83.33 mg/mL (199.58 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
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