ALK-IN-6


Catalog No. Size PriceQuantity
M30824-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

ALK-IN-6 (compound 11) is an orally bioavailable inhibitor of anaplastic lymphoma kinase (ALK), with IC50 values of 71 nM, 18.72 nM and 36.81 nM for ALK wild, ALK F1196M and ALK F1174L, respectively.

Product information

CAS Number: 2055821-33-3

Molecular Weight: 533.10

Formula: C26H32ClN5O3S

Chemical Name: 5-chloro-N2-[2-(²H₃)methoxy-5-methyl-4-(piperidin-4-yl)phenyl]-N4-[2-(propane-2-sulfonyl)phenyl]pyrimidine-2,4-diamine

Smiles: [2H]C([2H])([2H])OC1=CC(C2CCNCC2)=C(C)C=C1NC1N=CC(Cl)=C(NC2=CC=CC=C2S(=O)(=O)C(C)C)N=1

InChiKey: BXJYIWUWXJWABE-GKOSEXJESA-N

InChi: InChI=1S/C26H32ClN5O3S/c1-16(2)36(33,34)24-8-6-5-7-21(24)30-25-20(27)15-29-26(32-25)31-22-13-17(3)19(14-23(22)35-4)18-9-11-28-12-10-18/h5-8,13-16,18,28H,9-12H2,1-4H3,(H2,29,30,31,32)/i4D3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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