Dehydroascorbic acid


Catalog No. Size PriceQuantity
M30831-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Dehydroascorbic acid, a blood-brain barrier transportable form of vitamin C, mediates potent cerebroprotection in experimental stroke.

Product information

CAS Number: 490-83-5

Molecular Weight: 174.11

Formula: C6H6O6

Chemical Name: (5R)-5-[(1S)-1,2-dihydroxyethyl]oxolane-2,3,4-trione

Smiles: O[C@@H](CO)[C@H]1OC(=O)C(=O)C1=O

InChiKey: SBJKKFFYIZUCET-JLAZNSOCSA-N

InChi: InChI=1S/C6H6O6/c7-1-2(8)5-3(9)4(10)6(11)12-5/h2,5,7-8H,1H2/t2-,5+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: H2O : 5 mg/mL (28.72 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Neuronal injury in ischemic stroke is partly mediated by cytotoxic reactive oxygen species. Although the antioxidant ascorbic acid (AA) or vitamin C does not penetrate the blood-brain barrier (BBB), its oxidized form, dehydroascorbic acid (DHA), enters the brain by means of facilitative transport.

Products are for research use only. Not for human use.

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