Description
BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.
Product information
CAS Number: 2313524-95-5
Molecular Weight: 498.66
Formula: C32H38N2O3
Chemical Name: (2E)-3-(4-{4-[benzyl(ethyl)amino]butoxy}-3-methoxyphenyl)-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)prop-2-en-1-one
Smiles: COC1=CC(/C=C/C(=O)N2CC3=CC=CC=C3CC2)=CC=C1OCCCCN(CC1C=CC=CC=1)CC
InChiKey: CGZGXSZYVAXOGJ-FBMGVBCBSA-N
InChi: InChI=1S/C32H38N2O3/c1-3-33(24-27-11-5-4-6-12-27)20-9-10-22-37-30-17-15-26(23-31(30)36-2)16-18-32(35)34-21-19-28-13-7-8-14-29(28)25-34/h4-8,11-18,23H,3,9-10,19-22,24-25H2,1-2H3/b18-16+
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
Products are for research use only. Not for human use.
Payment & Security
Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.