BuChE-IN-TM-10


Catalog No. Size PriceQuantity
M31199-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

BuChE-IN-TM-10 (TM-10) is a potent butyrylcholinesterase (BuChE) inhibitor, with an IC50 of 8.9 nM. BuChE inhibitor 1 inhibits and disaggregates self-induced Aβ aggregation, exhibiting potent antioxidant activity and good blood-brain barrier (BBB) penetration. Has potential to treat Alzheimer’s disease.

Product information

CAS Number: 2313524-95-5

Molecular Weight: 498.66

Formula: C32H38N2O3

Chemical Name: (2E)-3-(4-{4-[benzyl(ethyl)amino]butoxy}-3-methoxyphenyl)-1-(1,2,3,4-tetrahydroisoquinolin-2-yl)prop-2-en-1-one

Smiles: COC1=CC(/C=C/C(=O)N2CC3=CC=CC=C3CC2)=CC=C1OCCCCN(CC1C=CC=CC=1)CC

InChiKey: CGZGXSZYVAXOGJ-FBMGVBCBSA-N

InChi: InChI=1S/C32H38N2O3/c1-3-33(24-27-11-5-4-6-12-27)20-9-10-22-37-30-17-15-26(23-31(30)36-2)16-18-32(35)34-21-19-28-13-7-8-14-29(28)25-34/h4-8,11-18,23H,3,9-10,19-22,24-25H2,1-2H3/b18-16+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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