IVHD-valtrate


Catalog No. Size PriceQuantity
M31870-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

IVHD-valtrate, an active Valeriana jatamansi derivative, is against human ovarian cancer cells in vitro and in vivo. IVHD-valtrate induces cancer cells apoptosis and arrests the ovarian cancer cells in the G2/M phase. IVHD-valtrate has the potential to be a novel chemotherapeutic agent for the human ovarian cancer research.

Product information

CAS Number: 28325-56-6

Molecular Weight: 540.60

Formula: C27H40O11

Chemical Name: [(1S,4aR,6S,7R,7aS)-6-(acetyloxy)-4a-hydroxy-1-[(3-methylbutanoyl)oxy]-4a,5,6,7a-tetrahydro-1H-spiro[cyclopenta[c]pyran-7,2'-oxiran]-4-yl]methyl 3-methyl-2-[(3-methylbutanoyl)oxy]butanoate

Smiles: CC(=O)O[C@H]1C[C@@]2(O)[C@H]([C@@H](OC=C2COC(=O)C(OC(=O)CC(C)C)C(C)C)OC(=O)CC(C)C)[C@]21CO2

InChiKey: QPMVBTMUWDUUTJ-KZYULCMASA-N

InChi: InChI=1S/C27H40O11/c1-14(2)8-20(29)37-22(16(5)6)24(31)33-11-18-12-34-25(38-21(30)9-15(3)4)23-26(18,32)10-19(36-17(7)28)27(23)13-35-27/h12,14-16,19,22-23,25,32H,8-11,13H2,1-7H3/t19-,22?,23-,25-,26-,27+/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

IVHD-valtrate inhibits the growth and proliferation of the A2780 and OVCAR-3 ovarian cancer cell lines in a concentration-dependent manner. IVHD-valtrate results in a relatively low cytotoxicity to immortalized non-tumorigenic human ovarian surface epithelial cells (IOSE-144).

Products are for research use only. Not for human use.

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