Description
Benzyl-PEG8-Ots is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Product information
CAS Number: 1144113-17-6
Molecular Weight: 614.74
Formula: C30H46O11S
Chemical Name: 1-phenyl-2,5,8,11,14,17,20,23-octaoxapentacosan-25-yl 4-methylbenzene-1-sulfonate
Smiles: CC1C=CC(=CC=1)S(=O)(=O)OCCOCCOCCOCCOCCOCCOCCOCCOCC1C=CC=CC=1
InChiKey: JZRYNAITFJTHLY-UHFFFAOYSA-N
InChi: InChI=1S/C30H46O11S/c1-28-7-9-30(10-8-28)42(31,32)41-26-25-39-22-21-37-18-17-35-14-13-33-11-12-34-15-16-36-19-20-38-23-24-40-27-29-5-3-2-4-6-29/h2-10H,11-27H2,1H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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