Description
Bis-methacrylate-PEG5 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 13497-24-0
Molecular Weight: 374.43
Formula: C18H30O8
Chemical Name: 14-[(2-methylprop-2-enoyl)oxy]-3,6,9,12-tetraoxatetradecan-1-yl 2-methylprop-2-enoate
Smiles: CC(=C)C(=O)OCCOCCOCCOCCOCCOC(=O)C(C)=C
InChiKey: HQKURBRFOOUSNI-UHFFFAOYSA-N
InChi: InChI=1S/C18H30O8/c1-15(2)17(19)25-13-11-23-9-7-21-5-6-22-8-10-24-12-14-26-18(20)16(3)4/h1,3,5-14H2,2,4H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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