DNP-PEG3-azide


Catalog No. Size PriceQuantity
M32153-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DNP-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 951671-87-7

Molecular Weight: 384.34

Formula: C14H20N6O7

Chemical Name: 1-(12-azido-4,7,10-trioxa-1-azadodecan-1-yl)-2,4-dinitrobenzene

Smiles: [N-]=[N+]=NCCOCCOCCOCCNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O

InChiKey: FIAOTUUAWJBUBV-UHFFFAOYSA-N

InChi: InChI=1S/C14H20N6O7/c15-18-17-4-6-26-8-10-27-9-7-25-5-3-16-13-2-1-12(19(21)22)11-14(13)20(23)24/h1-2,11,16H,3-10H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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