Description
DNP-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 951671-87-7
Molecular Weight: 384.34
Formula: C14H20N6O7
Chemical Name: 1-(12-azido-4,7,10-trioxa-1-azadodecan-1-yl)-2,4-dinitrobenzene
Smiles: [N-]=[N+]=NCCOCCOCCOCCNC1=CC=C(C=C1[N+]([O-])=O)[N+]([O-])=O
InChiKey: FIAOTUUAWJBUBV-UHFFFAOYSA-N
InChi: InChI=1S/C14H20N6O7/c15-18-17-4-6-26-8-10-27-9-7-25-5-3-16-13-2-1-12(19(21)22)11-14(13)20(23)24/h1-2,11,16H,3-10H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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