Phenol-amido-C1-PEG3-N3


Catalog No. Size PriceQuantity
M32174-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Phenol-amido-C1-PEG3-N3 (PROTAC Linker 21) is an PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Product information

CAS Number: 1096439-18-7

Molecular Weight: 324.33

Formula: C14H20N4O5

Chemical Name: 2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}-N-(4-hydroxyphenyl)acetamide

Smiles: [N-]=[N+]=NCCOCCOCCOCC(=O)NC1C=CC(O)=CC=1

InChiKey: UIVPCIQDQHNCCO-UHFFFAOYSA-N

InChi: InChI=1S/C14H20N4O5/c15-18-16-5-6-21-7-8-22-9-10-23-11-14(20)17-12-1-3-13(19)4-2-12/h1-4,19H,5-11H2,(H,17,20)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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