Boc-NH-PEG7-propargyl


Catalog No. Size PriceQuantity
M32277-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Boc-NH-PEG7-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2112737-90-1

Molecular Weight: 463.56

Formula: C22H41NO9

Chemical Name: tert-butyl N-(3,6,9,12,15,18,21-heptaoxatetracos-23-yn-1-yl)carbamate

Smiles: CC(C)(C)OC(=O)NCCOCCOCCOCCOCCOCCOCCOCC#C

InChiKey: KJDMOHBSNFYPKQ-UHFFFAOYSA-N

InChi: InChI=1S/C22H41NO9/c1-5-7-25-9-11-27-13-15-29-17-19-31-20-18-30-16-14-28-12-10-26-8-6-23-21(24)32-22(2,3)4/h1H,6-20H2,2-4H3,(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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