Hydroxy-PEG4-methyl acetate


Catalog No. Size PriceQuantity
M32355-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 77303-64-1

Molecular Weight: 266.29

Formula: C11H22O7

Chemical Name: methyl 14-hydroxy-3,6,9,12-tetraoxatetradecanoate

Smiles: COC(=O)COCCOCCOCCOCCO

InChiKey: CKNALYRJLYKSLK-UHFFFAOYSA-N

InChi: InChI=1S/C11H22O7/c1-14-11(13)10-18-9-8-17-7-6-16-5-4-15-3-2-12/h12H,2-10H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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