Description
Benzyl-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 127457-63-0
Molecular Weight: 268.31
Formula: C14H20O5
Chemical Name: 3-{2-[2-(benzyloxy)ethoxy]ethoxy}propanoic acid
Smiles: OC(=O)CCOCCOCCOCC1C=CC=CC=1
InChiKey: QCNCDLBZNNIXAQ-UHFFFAOYSA-N
InChi: InChI=1S/C14H20O5/c15-14(16)6-7-17-8-9-18-10-11-19-12-13-4-2-1-3-5-13/h1-5H,6-12H2,(H,15,16)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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