Azido-PEG3-Sulfone-PEG4-acid


Catalog No. Size PriceQuantity
M32414-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Azido-PEG3-Sulfone-PEG4-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055024-42-3

Molecular Weight: 515.58

Formula: C19H37N3O11S

Chemical Name: 1-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethanesulfonyl)-3,6,9,12-tetraoxapentadecan-15-oic acid

Smiles: [N-]=[N+]=NCCOCCOCCOCCS(=O)(=O)CCOCCOCCOCCOCCC(O)=O

InChiKey: WDRWRFOESMUATQ-UHFFFAOYSA-N

InChi: InChI=1S/C19H37N3O11S/c20-22-21-2-4-28-6-8-30-11-13-32-15-17-34(25,26)18-16-33-14-12-31-10-9-29-7-5-27-3-1-19(23)24/h1-18H2,(H,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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