Description
BDP FL-PEG4-amine is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 2183473-14-3
Molecular Weight: 510.38
Formula: C24H37BF2N4O5
Chemical Name: 4-{2-[(14-amino-3,6,9,12-tetraoxatetradecan-1-yl)carbamoyl]ethyl}-2,2-difluoro-10,12-dimethyl-1λ⁵,3-diaza-2-boratricyclo[7.3.0.0³,⁷]dodeca-1(12),4,6,8,10-pentaen-1-ylium-2-uide
Smiles: CC1C=C(C)C2=CC3=CC=C(CCC(=O)NCCOCCOCCOCCOCCN)N3[B-](F)(F)[N+]=12
InChiKey: AYCLOPCACPMSPT-UHFFFAOYSA-N
InChi: InChI=1S/C24H37BF2N4O5/c1-19-17-20(2)30-23(19)18-22-4-3-21(31(22)25(30,26)27)5-6-24(32)29-8-10-34-12-14-36-16-15-35-13-11-33-9-7-28/h3-4,17-18H,5-16,28H2,1-2H3,(H,29,32)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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