Bromoacetamido-PEG8-Boc


Catalog No. Size PriceQuantity
M32580-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bromoacetamido-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2055041-16-0

Molecular Weight: 618.55

Formula: C25H48BrNO11

Chemical Name: tert-butyl 1-(2-bromoacetamido)-3,6,9,12,15,18,21,24-octaoxaheptacosan-27-oate

Smiles: CC(C)(C)OC(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CBr

InChiKey: BPWCFBGOCYWQSQ-UHFFFAOYSA-N

InChi: InChI=1S/C25H48BrNO11/c1-25(2,3)38-24(29)4-6-30-8-10-32-12-14-34-16-18-36-20-21-37-19-17-35-15-13-33-11-9-31-7-5-27-23(28)22-26/h4-22H2,1-3H3,(H,27,28)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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