Description
Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs.
Product information
CAS Number: 1351397-21-1
Molecular Weight: 355.43
Formula: C18H29NO6
Chemical Name: benzyl 1-amino-3,6,9,12-tetraoxapentadecan-15-oate
Smiles: NCCOCCOCCOCCOCCC(=O)OCC1C=CC=CC=1
InChiKey: MNJPPZOECOMFQW-UHFFFAOYSA-N
InChi: InChI=1S/C18H29NO6/c19-7-9-22-11-13-24-15-14-23-12-10-21-8-6-18(20)25-16-17-4-2-1-3-5-17/h1-5H,6-16,19H2
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
Products are for research use only. Not for human use.
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