Bis-PEG7-PFP ester


Catalog No. Size PriceQuantity
M32623-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Bis-PEG7-PFP ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 1334170-01-2

Molecular Weight: 758.55

Formula: C30H32F10O11

Chemical Name: bis(2,3,4,5,6-pentafluorophenyl) 4,7,10,13,16,19,22-heptaoxapentacosanedioate

Smiles: O=C(CCOCCOCCOCCOCCOCCOCCOCCC(=O)OC1=C(F)C(F)=C(F)C(F)=C1F)OC1=C(F)C(F)=C(F)C(F)=C1F

InChiKey: NEFPGEFWBAKGRR-UHFFFAOYSA-N

InChi: InChI=1S/C30H32F10O11/c31-19-21(33)25(37)29(26(38)22(19)34)50-17(41)1-3-43-5-7-45-9-11-47-13-15-49-16-14-48-12-10-46-8-6-44-4-2-18(42)51-30-27(39)23(35)20(32)24(36)28(30)40/h1-16H2

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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