Acid-PEG2-C2-Boc


Catalog No. Size PriceQuantity
M32640-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Acid-PEG2-C2-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2086688-99-3

Molecular Weight: 262.30

Formula: C12H22O6

Chemical Name: 3-{2-[3-(tert-butoxy)-3-oxopropoxy]ethoxy}propanoic acid

Smiles: CC(C)(C)OC(=O)CCOCCOCCC(O)=O

InChiKey: FVMOAKLTZMCDOV-UHFFFAOYSA-N

InChi: InChI=1S/C12H22O6/c1-12(2,3)18-11(15)5-7-17-9-8-16-6-4-10(13)14/h4-9H2,1-3H3,(H,13,14)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (381.24 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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