DSPE-PEG5-propargyl


Catalog No. Size PriceQuantity
M32699-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DSPE-PEG5-propargyl is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2112737-93-4

Molecular Weight: 1034.39

Formula: C55H104NO14P

Chemical Name: [(2R)-2,3-bis(octadecanoyloxy)propoxy][2-(4,7,10,13,16-pentaoxanonadec-18-ynamido)ethoxy]phosphinic acid

Smiles: CCCCCCCCCCCCCCCCCC(=O)OC[C@H](COP(O)(=O)OCCNC(=O)CCOCCOCCOCCOCCOCC#C)OC(=O)CCCCCCCCCCCCCCCCC

InChiKey: TWBDHVREIJJEGS-OIVUAWODSA-N

InChi: InChI=1S/C55H104NO14P/c1-4-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-54(58)67-50-52(70-55(59)36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-5-2)51-69-71(60,61)68-41-38-56-53(57)37-40-63-43-45-65-47-49-66-48-46-64-44-42-62-39-6-3/h3,52H,4-5,7-51H2,1-2H3,(H,56,57)(H,60,61)/t52-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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