Description
DMAC-SPDB-sulfo is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663599-07-3
Molecular Weight: 477.53
Formula: C16H19N3O8S3
Chemical Name: 1-[(4-{[5-(dimethylcarbamoyl)pyridin-2-yl]disulfanyl}butanoyl)oxy]-2,5-dioxopyrrolidine-3-sulfonic acid
Smiles: CN(C)C(=O)C1=CN=C(C=C1)SSCCCC(=O)ON1C(=O)C(CC1=O)S(O)(=O)=O
InChiKey: KMRAQLKAJPMTOK-UHFFFAOYSA-N
InChi: InChI=1S/C16H19N3O8S3/c1-18(2)15(22)10-5-6-12(17-9-10)29-28-7-3-4-14(21)27-19-13(20)8-11(16(19)23)30(24,25)26/h5-6,9,11H,3-4,7-8H2,1-2H3,(H,24,25,26)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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