endo-BCN-PEG3-mal


Catalog No. Size PriceQuantity
M32733-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

endo-BCN-PEG3-mal is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Product information

CAS Number: 2141976-33-0

Molecular Weight: 519.59

Formula: C26H37N3O8

Chemical Name: [(1R,8S)-bicyclo[6.1.0]non-4-yn-9-yl]methyl N-{2-[2-(2-{2-[3-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)propanamido]ethoxy}ethoxy)ethoxy]ethyl}carbamate

Smiles: O=C(CCN1C(=O)C=CC1=O)NCCOCCOCCOCCNC(=O)OCC1[C@H]2CCC#CCC[C@H]21

InChiKey: ZZRUYTQNTVMKLG-CBQGHPETSA-N

InChi: InChI=1S/C26H37N3O8/c30-23(9-12-29-24(31)7-8-25(29)32)27-10-13-34-15-17-36-18-16-35-14-11-28-26(33)37-19-22-20-5-3-1-2-4-6-21(20)22/h7-8,20-22H,3-6,9-19H2,(H,27,30)(H,28,33)/t20-,21+,22?

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

Products are for research use only. Not for human use.

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