DBCO-Sulfo-NHS ester sodium

DBCO-Sulfo-NHS ester sodium is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Product information

CAS Number: 1400191-52-7

Molecular Weight: 532.50

Formula: C25H21N2NaO8S

Chemical Name: sodium 1-[(6-{2-azatricyclo[10.4.0.0⁴,⁹]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl}-6-oxohexanoyl)oxy]-2,5-dioxopyrrolidine-3-sulfonate

Smiles: [Na+].[O-]S(=O)(=O)C1CC(=O)N(OC(=O)CCCCC(=O)N2CC3=CC=CC=C3C#CC3=CC=CC=C23)C1=O

InChiKey: QXKHPYSXPCJSPR-UHFFFAOYSA-M

InChi: InChI=1S/C25H22N2O8S.Na/c28-22(11-5-6-12-24(30)35-27-23(29)15-21(25(27)31)36(32,33)34)26-16-19-9-2-1-7-17(19)13-14-18-8-3-4-10-20(18)26;/h1-4,7-10,21H,5-6,11-12,15-16H2,(H,32,33,34);/q;+1/p-1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Products are for research use only. Not for human use.