Description
4-Hydroxymephenytoin is a metabolism of an antiepileptic drug mephenytoin, which is used as a CYP2C19 substrate.
Product information
CAS Number: 61837-65-8
Molecular Weight: 234.25
Formula: C12H14N2O3
Chemical Name: 5-ethyl-5-(4-hydroxyphenyl)-3-methylimidazolidine-2,4-dione
Smiles: CCC1(NC(=O)N(C)C1=O)C1C=CC(O)=CC=1
InChiKey: OQPLORUDZLXXPD-UHFFFAOYSA-N
InChi: InChI=1S/C12H14N2O3/c1-3-12(8-4-6-9(15)7-5-8)10(16)14(2)11(17)13-12/h4-7,15H,3H2,1-2H3,(H,13,17)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (426.89 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
4-Hydroxymephenytoin is a metabolism of mephenytoin, which is an antiepileptic drug, and used as a CYP2C19 substrate. 4-Hydroxymephenytoin (4'-Hydroxymephenytoin) is used for developing UltraPerformance LC (UPLC) tandem mass spectrometry assays for evaluating CYP probe drugs and their relevant metabolites in human urine or plasma samples.
Products are for research use only. Not for human use.
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