Description
DMAC-SPP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
Product information
CAS Number: 663599-10-8
Molecular Weight: 411.50
Formula: C17H21N3O5S2
Chemical Name: 2,5-dioxopyrrolidin-1-yl 4-{[3-(dimethylcarbamoyl)pyridin-4-yl]disulfanyl}pentanoate
Smiles: CN(C)C(=O)C1=CN=CC=C1SSC(C)CCC(=O)ON1C(=O)CCC1=O
InChiKey: AFGUQHOCEUTKEQ-UHFFFAOYSA-N
InChi: InChI=1S/C17H21N3O5S2/c1-11(4-7-16(23)25-20-14(21)5-6-15(20)22)26-27-13-8-9-18-10-12(13)17(24)19(2)3/h8-11H,4-7H2,1-3H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
Products are for research use only. Not for human use.
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