Description
Ikarugamycin is an antibiotic and a inhibitor of clathrin-mediated endocytosis (CME).
Product information
CAS Number: 36531-78-9
Molecular Weight: 478.62
Formula: C29H38N2O4
Chemical Name: (5S,7R,8R,10R,11R,12S,15R,16S,25S)-11-ethyl-2-hydroxy-10-methyl-21,26-diazapentacyclo[23.2.1.0⁵,¹⁶.0⁷,¹⁵.0⁸,¹²]octacosa-1,3,13,18-tetraene-20,27,28-trione
Smiles: C[C@@H]1C[C@H]2[C@@H](C=C[C@@H]3[C@H]4CC=CC(=O)NCCC[C@@H]5NC(=O)C(=C(O)C=C[C@@H]4C[C@@H]32)C5=O)[C@@H]1CC |c:10,22,t:25|
InChiKey: GHXZHWYUSAWISC-YKORYBRQSA-N
InChi: InChI=1S/C29H38N2O4/c1-3-18-16(2)14-22-20(18)10-11-21-19-6-4-8-26(33)30-13-5-7-24-28(34)27(29(35)31-24)25(32)12-9-17(19)15-23(21)22/h4,8-12,16-24,32H,3,5-7,13-15H2,1-2H3,(H,30,33)(H,31,35)/b8-4-,12-9-,27-25-/t16-,17-,18-,19+,20+,21-,22+,23+,24+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Ikarugamycin has an IC50 of 2.7 μM in H1299 cells.
Products are for research use only. Not for human use.
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