Description
Ganodermanontriol, a sterol isolated from Ganoderma lucidum, induces anti-inflammatory activity in tert-butyl hydroperoxide (t-BHP)-damaged hepatic cells through the expression of HO-1. Ganodermanontriol exhibits hepatoprotective activity.
Product information
CAS Number: 106518-63-2
Molecular Weight: 472.70
Formula: C30H48O4
Chemical Name: (1R,3aR,5aR,9aS,11aR)-3a,6,6,9a,11a-pentamethyl-1-[(2R,5S)-5,6,7-trihydroxy-6-methylheptan-2-yl]-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthren-7-one
Smiles: CC1(C)[C@@H]2CC=C3C(=CC[C@]4(C)[C@H](CC[C@]43C)[C@H](C)CC[C@H](O)C(C)(O)CO)[C@@]2(C)CCC1=O
InChiKey: KASALCUNLBTNAA-VIKWRQSJSA-N
InChi: InChI=1S/C30H48O4/c1-19(8-11-25(33)30(7,34)18-31)20-12-16-29(6)22-9-10-23-26(2,3)24(32)14-15-27(23,4)21(22)13-17-28(20,29)5/h9,13,19-20,23,25,31,33-34H,8,10-12,14-18H2,1-7H3/t19-,20-,23+,25+,27-,28-,29+,30?/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Ganodermanontriol inhibits breast cancer cell lines MCF-7 and MDA-MB-231with IC50 values of 5.8 and 9.7 μM, respectively.
Products are for research use only. Not for human use.
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