Description
Alminoprofen (EB-382) is a nonsteroidal anti-inflammatory drug (NSAID) of the phenylpropionic acid class. Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both secretory phospholipase A2 (sPLA2) and COX-2.
Product information
CAS Number: 39718-89-3
Molecular Weight: 219.28
Formula: C13H17NO2
Chemical Name: 2-{4-[(2-methylprop-2-en-1-yl)amino]phenyl}propanoic acid
Smiles: CC(=C)CNC1C=CC(=CC=1)C(C)C(O)=O
InChiKey: FPHLBGOJWPEVME-UHFFFAOYSA-N
InChi: InChI=1S/C13H17NO2/c1-9(2)8-14-12-6-4-11(5-7-12)10(3)13(15)16/h4-7,10,14H,1,8H2,2-3H3,(H,15,16)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Alminoprofen possesses a dual anti-inflammatory action, by inhibiting both sPLA2 but also COX-2. Alminoprofen (from 0 to 50 μM) induces a dose-related inhibitory response on thelevels of PGE2 formed by the CRL-1517 cell line.
In Vivo:
Alminoprofen (100-300 mg/kg; p.o.) exerts an anti-inflammatory activity.
Products are for research use only. Not for human use.
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