Diphenylpyraline


Catalog No. Size PriceQuantity
M33274-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

Diphenylpyraline is a potent histamine H1 receptor antagonist. Diphenylpyraline acts as an orally active antihistamine agent with antimuscarinic and antiallergic effects. Diphenylpyraline can be used for the research of allergic diseases, including rhinitis and hay fever, and pruritic skin disorders et.al.

Product information

CAS Number: 147-20-6

Molecular Weight: 281.39

Formula: C19H23NO

Chemical Name: 4-(diphenylmethoxy)-1-methylpiperidine

Smiles: CN1CCC(CC1)OC(C1=CC=CC=C1)C1=CC=CC=C1

InChiKey: OWQUZNMMYNAXSL-UHFFFAOYSA-N

InChi: InChI=1S/C19H23NO/c1-20-14-12-18(13-15-20)21-19(16-8-4-2-5-9-16)17-10-6-3-7-11-17/h2-11,18-19H,12-15H2,1H3

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (355.38 mM; Need ultrasonic). H2O : < 0.1 mg/mL (insoluble).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Diphenylpyraline (10 μM) markedly inhibits dopamine uptakein mouse nucleus accumbens slices.

In Vivo:

Diphenylpyraline (intraperitoneal injection; 5-10 mg/kg) elevates extracellular dopamine levels (~200%) in mouse nucleus accumbens and induces locomotor activation in mice.

Products are for research use only. Not for human use.

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