Description
LDL-IN-3 is an anti-atherosclerotic compound extracted from patent WO/2005/039596A1, example C25 and patent US 6133467, example 3.
Product information
CAS Number: 180908-67-2
Molecular Weight: 400.63
Formula: C24H36O3Si
Chemical Name: 2,6-di-tert-butyl-4-{[(4-methoxyphenyl)dimethylsilyl]methoxy}phenol
Smiles: COC1C=CC(=CC=1)[Si](C)(C)COC1=CC(=C(O)C(=C1)C(C)(C)C)C(C)(C)C
InChiKey: PJKUTMONJXDZNR-UHFFFAOYSA-N
InChi: InChI=1S/C24H36O3Si/c1-23(2,3)20-14-18(15-21(22(20)25)24(4,5)6)27-16-28(8,9)19-12-10-17(26-7)11-13-19/h10-15,25H,16H2,1-9H3
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
LDL-IN-3 is antioxidant which inhibits low density lipoprotein (LDL) lipid peroxidation and is useful as anti-atherosclerotic agents.
In Vivo:
LDL-IN-3 decreases serum cholesterol, TBARS and the amount of aortic lesions (57 %) in comparison with control rabbits. LDL-IN-3 is found in very high concentrations in the serum (182.4 μg/mL) and livers (323 μg/mL).
Products are for research use only. Not for human use.
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