DLinDMA


Catalog No. Size PriceQuantity
M33291-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

DLinDMA, a ionizable cationic lipid, is a key lipid component of stable nucleic acid lipid particles (SNALPs) as a benchmark. DLinDMA is used for siRNA delivery.

Product information

CAS Number: 871258-12-7

Molecular Weight: 616.06

Formula: C41H77NO2

Chemical Name: {2,3-bis[(9Z,12Z)-octadeca-9,12-dien-1-yloxy]propyl}dimethylamine

Smiles: CN(C)CC(COCCCCCCCC/C=C\C/C=C\CCCCC)OCCCCCCCC/C=C\C/C=C\CCCCC

InChiKey: NFQBIAXADRDUGK-KWXKLSQISA-N

InChi: InChI=1S/C41H77NO2/c1-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-35-37-43-40-41(39-42(3)4)44-38-36-34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-2/h13-16,19-22,41H,5-12,17-18,23-40H2,1-4H3/b15-13-,16-14-,21-19-,22-20-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 3 mg/mL (4.87 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

The structure of DLinDMA can be divided into three main regions: the hydrocarbon chains, the linker and the headgroup.

In Vivo:

DLinDMA has virtually indistinguishable blood pharmacokinetic profiles in mice.

Products are for research use only. Not for human use.

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