RPH-2823


Catalog No. Size PriceQuantity
M33373-C Contact sales@xcessbio.com for quotation $100Unavailable

Description

RPH-2823, a basic triamterene derivative, induces a dose-dependent decrease in short-circuit current (SCC) and increase in transepithelial electrical resistance.

Product information

CAS Number: 96558-24-6

Molecular Weight: 370.41

Formula: C17H22N8O2

Chemical Name: 1-(dimethylamino)-3-[4-(2,4,7-triaminopteridin-6-yl)phenoxy]propan-2-ol

Smiles: CN(C)CC(O)COC1C=CC(=CC=1)C1=NC2=C(N=C1N)N=C(N)N=C2N

InChiKey: DREYSFUKNSYCCL-UHFFFAOYSA-N

InChi: InChI=1S/C17H22N8O2/c1-25(2)7-10(26)8-27-11-5-3-9(4-6-11)12-14(18)22-16-13(21-12)15(19)23-17(20)24-16/h3-6,10,26H,7-8H2,1-2H3,(H6,18,19,20,22,23,24)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

RPH-2823 influences transepithelial Na+ transport by interacting with the Na+ channel or a regulator site of it within the apical membrane.

In Vivo:

RPH 2823 (2.5 mumol/kg) can avoid the kaliuresis of 25 mumol/kg furosemide in male Wistar rats. RPH 2823 (1 mg/kg and 5 mg/kg, i.v.) has a terminal elimination half-life of 3 h. About 47% of the given dose are excreted unchanged with urine.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

You may also like

Recently viewed