10-Formylfolic acid


Catalog No. Size PriceQuantity
M33870-C Contact sales@xcessbio.com for quotation $100

Description

10-Formylfolic acid is a potent inhibitor of dihydrofolate reductase.

Product information

CAS Number: 134-05-4

Molecular Weight: 469.41

Formula: C20H19N7O7

Chemical Name: (4-(N-((2-amino-4-oxo-1, 4-dihydropteridin-6-yl)methyl)formamido)benzoyl)-L-glutamic acid

Smiles: NC1NC2=NC=C(CN(C=O)C3C=CC(=CC=3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N=C2C(=O)N=1

InChiKey: UGWUWNVTCLDEOG-ZDUSSCGKSA-N

InChi: InChI=1S/C20H19N7O7/c21-20-25-16-15(18(32)26-20)23-11(7-22-16)8-27(9-28)12-3-1-10(2-4-12)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,7,9,13H,5-6,8H2,(H,24,31)(H,29,30)(H,33,34)(H3,21,22,25,26,32)/t13-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Ashokkumar K, Sivakumar P, Saradhadevi M. Identification and determination of naturally occurring folates in grains of rice (Oryza sativa L.) by UPLC-MS/MS analysis. Nat Prod Res. 2018 Jul;32(14):1733-1737. doi: 10.1080/14786419.2017.1392957. Epub 2017 Oct 23. PubMed PMID: 29058482.
  2. Kopp M, Morisset R, Rychlik M. Characterization and Interrelations of One-Carbon Metabolites in Tissues, Erythrocytes, and Plasma in Mice with Dietary Induced Folate Deficiency. Nutrients. 2017 May 5;9(5). pii: E462. doi: 10.3390/nu9050462. PubMed PMID: 28475162; PubMed Central PMCID: PMC5452192.
  3. Kopp M, Dürr K, Steigleder M, Clavel T, Rychlik M. Development of stable isotope dilution assays for the quantitation of intra- and extracellular folate patterns of Bifidobacterium adolescentis. J Chromatogr A. 2016 Oct 21;1469:48-59. doi: 10.1016/j.chroma.2016.09.048. Epub 2016 Sep 22. PubMed PMID: 27692648.

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed