PTPN22-IN-1


Catalog No. Size PriceQuantity
M33895-C Contact sales@xcessbio.com for quotation $100

Description

PTPN22-IN-1 is a potent PTPN22 inhibitor (IC50=1.4 µM; Ki=0.50 µM). PTPN22-IN-1 exhibits >7-10 fold selectivity for PTPN22 over similar phosphatases. PTPN22-IN-1 augments antitumor immune responses. From WO2021007491A1 compound L-1.

Product information

CAS Number: 2580935-57-3

Molecular Weight: 455.46

Formula: C26H21N3O5

Smiles: C[C@H](NC(=O)C1C=CC(=CC=1)C1C=CC=CC=1)C(=O)NC1=CC2=C(C=C1)NC=C(C(O)=O)C2=O

InChiKey: PBKUVBJIDJIKJJ-HNNXBMFYSA-N

InChi: InChI=1S/C26H21N3O5/c1-15(28-25(32)18-9-7-17(8-10-18)16-5-3-2-4-6-16)24(31)29-19-11-12-22-20(13-19)23(30)21(14-27-22)26(33)34/h2-15H,1H3,(H,27,30)(H,28,32)(H,29,31)(H,33,34)/t15-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Elizabeth Jaffee, et al. Targeting ptpn22 in cancer therapy. WO2021007491A1.

Products are for research use only. Not for human use.

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