POP-IN-2


Catalog No. Size PriceQuantity
M33942-C Contact sales@xcessbio.com for quotation $100

Description

POP-IN-2 (Compound 7k) is a potent, covalent prolyl oligopeptidase (POP) inhibitor with a Ki of 6 nM. POP-IN-2 can be used for studying neurodegenerative diseases and cancer.

Product information

CAS Number: 2743432-81-5

Molecular Weight: 440.34

Formula: C24H33BN2O5

Smiles: CC1(C)[C@@H]2C[C@H]1C[C@H]1OB(O[C@]12C)C1CCCN1C(=O)C1=CC=C(C=C1OC)NC(C)=O

InChiKey: AKWLBANFCWCWKL-MFNWNAFKSA-N

InChi: InChI=1S/C24H33BN2O5/c1-14(28)26-16-8-9-17(18(13-16)30-5)22(29)27-10-6-7-21(27)25-31-20-12-15-11-19(23(15,2)3)24(20,4)32-25/h8-9,13,15,19-21H,6-7,10-12H2,1-5H3,(H,26,28)/t15-,19-,20+,21?,24-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Jessica Plescia, et al. Discovery of covalent prolyl oligopeptidase boronic ester inhibitors. Eur J Med Chem. 2020 Jan 1;185:111783.

Products are for research use only. Not for human use.

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