SP-187 HCl


Catalog No. Size PriceQuantity
M34013-C Contact sales@xcessbio.com for quotation $100

Description

SP-187, also known as N-9-DNJ and UV-4B, is an alpha-Glucosidase inhibitor potentially for the treatment of dengue fever and influenza infection. Proline-producing strains of Serratia marcescens were more osmotolerant than wild-type strains. Growth inhibition by proline analogs was significantly enhanced by increasing the osmotic stress of the medium.

Product information

CAS Number: 1333144-07-2

Molecular Weight: 355.90

Formula: C16H34ClNO5

Chemical Name: (2R, 3R, 4R, 5S)-2-(hydroxymethyl)-1-(9-methoxynonyl)piperidine-3, 4, 5-triol hydrochloride

Smiles: Cl.COCCCCCCCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO

InChiKey: LQFACEKDJKFAIT-NUSSTLEHSA-N

InChi: InChI=1S/C16H33NO5.ClH/c1-22-10-8-6-4-2-3-5-7-9-17-11-14(19)16(21)15(20)13(17)12-18;/h13-16,18-21H,2-12H2,1H3;1H/t13-,14+,15-,16-;/m1./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Sugiura M, Kisumi M. Proline-hyperproducing strains of Serratia marcescens: enhancement of proline analog-mediated growth inhibition by increasing osmotic stress. Appl Environ Microbiol. 1985 Apr;49(4):782-6. PubMed PMID: 2860849; PubMed Central PMCID: PMC238445.
  2. Baba E, Nakamura M, Ohkuma K, Kira J, Tanaka Y, Nakano S, Niho Y. A peptide-based human T cell leukemia virus type I vaccine containing T and B cell epitopes that induces high titers of neutralizing antibodies. J Immunol. 1995 Jan 1;154(1):399-412. PubMed PMID: 7527817.

Products are for research use only. Not for human use.

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