Glycovir


Catalog No. Size PriceQuantity
M34017-C Contact sales@xcessbio.com for quotation $100

Description

Glycovir, also known as SC-49483, is an anti-HIV prodrug. Glycovir is an alpha-glucosidase-1 inhibitor, and a candidate anti-HIV agent targeted against viral glycoprotein processing in host cell endoplasmic reticulum.

Product information

CAS Number: 131262-82-3

Molecular Weight: 499.64

Formula: C26H45NO8

Chemical Name: (2R, 3R, 4R, 5S)-1-butyl-2-((butyryloxy)methyl)piperidine-3, 4, 5-triyl tributyrate

Smiles: CCCCN1C[C@H](OC(=O)CCC)[C@@H](OC(=O)CCC)[C@H](OC(=O)CCC)[C@H]1COC(=O)CCC

InChiKey: MKGDNVHZSCXBKR-KYVQNOJUSA-N

InChi: InChI=1S/C26H45NO8/c1-6-11-16-27-17-20(33-22(29)13-8-3)26(35-24(31)15-10-5)25(34-23(30)14-9-4)19(27)18-32-21(28)12-7-2/h19-20,25-26H,6-18H2,1-5H3/t19-,20+,25-,26-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: To be determined

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

  1. Khan KN, Snook SS, Semler DE, Baron DA, Alden CL. Pathology of perbutylated- N-butyl-1-deoxynojiromycin (an alpha-glucosidase-1 inhibitor) in Sprague-Dawley rats. Toxicol Pathol. 1996 Sep-Oct;24(5):531-8. doi: 10.1177/019262339602400501. PMID: 8923673.
  2. Cook CS, Karabatsos PJ, Schoenhard GL, Karim A. Species dependent esterase activities for hydrolysis of an anti-HIV prodrug glycovir and bioavailability of active SC-48334. Pharm Res. 1995 Aug;12(8):1158-64. doi: 10.1023/a:1016259826037. PMID: 7494828.

Products are for research use only. Not for human use.

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