Description
Cholic acid-d5 is the deuterium labeled Cholic acid. Cholic acid is a major primary bile acid produced in the liver and usually conjugated with glycine or taurine. It facilitates fat absorption and cholesterol excretion.
Product information
CAS Number: 53007-09-3
Molecular Weight: 413.60
Formula: C24H40O5
Chemical Name: (4R)-4-[(1R,3aS,3bR,4R,5aR,7R,9aS,9bS,11S,11aR)-4,7,11-trihydroxy-9a,11a-dimethyl-hexadecahydro(6,6,7,8,8-²H₅)-1H-cyclopenta[a]phenanthren-1-yl]pentanoic acid
Smiles: [2H][C@]1(O)C([2H])([2H])[C@H]2C[C@@H](O)[C@@H]3[C@H](C[C@H](O)[C@]4(C)[C@H](CC[C@H]43)[C@H](C)CCC(O)=O)[C@@]2(C)CC1([2H])[2H]
InChiKey: BHQCQFFYRZLCQQ-VRLVFLRJSA-N
InChi: InChI=1S/C24H40O5/c1-13(4-7-21(28)29)16-5-6-17-22-18(12-20(27)24(16,17)3)23(2)9-8-15(25)10-14(23)11-19(22)26/h13-20,22,25-27H,4-12H2,1-3H3,(H,28,29)/t13-,14+,15-,16-,17+,18+,19-,20+,22+,23+,24-/m1/s1/i8D2,10D2,15D
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : ≥ 50 mg/mL (120.89 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO). H2O : 0.67 mg/mL (1.62 mM; Need ultrasonic).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
Products are for research use only. Not for human use.
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