VU6010572


Catalog No. Size PriceQuantity
M34802-C Contact sales@xcessbio.com for quotation $100

Description

VU6010572 is a potent and selective mGlu3 negative allosteric modulator with IC50 of 245 nM. VU6010572 is highly CNS penetrant.

Product information

CAS Number: 2126784-39-0

Molecular Weight: 339.36

Formula: C20H18FNO3

Chemical Name: 1-(4-fluorophenyl)-4-[(2S)-2-phenoxypropoxy]-1,2-dihydropyridin-2-one

Smiles: C[C@@H](COC1=CC(=O)N(C=C1)C1=CC=C(F)C=C1)OC1C=CC=CC=1

InChiKey: AUMJXOXUSGIUCB-HNNXBMFYSA-N

InChi: InChI=1S/C20H18FNO3/c1-15(25-18-5-3-2-4-6-18)14-24-19-11-12-22(20(23)13-19)17-9-7-16(21)8-10-17/h2-13,15H,14H2,1H3/t15-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 100 mg/mL (294.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

VU6010572 (3 mg/kg; i.p.) shows robust efficacy. VU6010572 (3 mg/kg; i.p.; 45 minutes) produces lasting anxiolytic-like behavioral effects.

Products are for research use only. Not for human use.

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