(R)-MLN-4760


Catalog No. Size PriceQuantity
M34810-C Contact sales@xcessbio.com for quotation $100

Description

(R)-MLN-4760, the R-enantiomer of MLN-4760, is an ACE2 inhibitor, with an IC50 of 8.4 μM. (R)-MLN-4760 is the less active isomer.

Product information

CAS Number: 305335-29-9

Molecular Weight: 428.31

Formula: C19H23Cl2N3O4

Chemical Name: (2R)-2-{[(1S)-1-carboxy-2-{1-[(3,5-dichlorophenyl)methyl]-1H-imidazol-5-yl}ethyl]amino}-4-methylpentanoic acid

Smiles: CC(C)C[C@@H](N[C@@H](CC1=CN=CN1CC1C=C(Cl)C=C(Cl)C=1)C(O)=O)C(O)=O

InChiKey: NTCCRGGIJNDEAB-SJORKVTESA-N

InChi: InChI=1S/C19H23Cl2N3O4/c1-11(2)3-16(18(25)26)23-17(19(27)28)7-15-8-22-10-24(15)9-12-4-13(20)6-14(21)5-12/h4-6,8,10-11,16-17,23H,3,7,9H2,1-2H3,(H,25,26)(H,27,28)/t16-,17+/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 14.29 mg/mL (33.36 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

(R)-MLN-4760 (compound 16RS) is the less active isomer of MLN-4760.

Products are for research use only. Not for human use.

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