GPR30 agonist-1


Catalog No. Size PriceQuantity
M34847-C Contact sales@xcessbio.com for quotation $100

Description

GPR30 agonist-1 is a G protein-coupled receptor 30 (GPR30) agonist. GPR30 agonist-1 exerts vasorelaxant effects.

Product information

CAS Number: 415919-74-3

Molecular Weight: 374.25

Formula: C19H17BrFNO

Chemical Name: (3aS,4R,9bR)-4-(5-bromo-2-methoxyphenyl)-8-fluoro-3H,3aH,4H,5H,9bH-cyclopenta[c]quinoline

Smiles: COC1=CC=C(Br)C=C1[C@@H]1NC2=CC=C(F)C=C2[C@@H]2C=CC[C@H]12

InChiKey: YGLAUQAYNBUDIJ-BIENJYKASA-N

InChi: InChI=1S/C19H17BrFNO/c1-23-18-8-5-11(20)9-16(18)19-14-4-2-3-13(14)15-10-12(21)6-7-17(15)22-19/h2-3,5-10,13-14,19,22H,4H2,1H3/t13-,14+,19-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (133.60 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

GPR30 agonist-1 (compound 5408-0877) (1 nM-10 μM) induces a concentration-dependent relaxation in carotid arteries from both male and female rats. GPR30 agonist-1-induced relaxation is abolished by endothelium removal and abrogated in the presence of the nitric oxide synthase inhibitor NG-nitro-l-arginine methyl ester (100 μM).

Products are for research use only. Not for human use.

Payment & Security

PayPal Venmo

Your payment information is processed securely. We do not store credit card details nor have access to your credit card information.

Estimate shipping

You may also like

Recently viewed