Description
Golgicide A-2 (GCA-2), a Golgicide A (GCA) derivative, is the most active enantiomer of GCA. Golgicide A-2 displays high selectivity and efficiency in killing An. stephensi larvae and can be used for the research of dengue virus related diseases.
Product information
CAS Number: 1394285-50-7
Molecular Weight: 284.30
Formula: C17H14F2N2
Chemical Name: 3-[(3aS,4R,9bR)-6,8-difluoro-3H,3aH,4H,5H,9bH-cyclopenta[c]quinolin-4-yl]pyridine
Smiles: FC1C=C2[C@@H]3C=CC[C@@H]3[C@@H](NC2=C(F)C=1)C1C=CC=NC=1
InChiKey: NJZHEQOUHLZCOX-WWGRRREGSA-N
InChi: InChI=1S/C17H14F2N2/c18-11-7-14-12-4-1-5-13(12)16(10-3-2-6-20-9-10)21-17(14)15(19)8-11/h1-4,6-9,12-13,16,21H,5H2/t12-,13+,16+/m1/s1
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Solubility: DMSO : 100 mg/mL (351.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO).
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vitro:
GCA-2 is effective in killing both Ae. Aegypti and An. Stephensi larvae, while it is displays distinct and strongly selective cytotoxicity towards Ae. Stephensi larvae with a mortality of 83.4%.
Products are for research use only. Not for human use.
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