5-Hydroxymethyldeoxyuridine

5-Hydroxymethyldeoxyuridine is a nucleoside analog with anticancer and antiviral activities. It inhibits the replication of murine S180 lung carcinoma cells and Ehrlich ascites mammary carcinoma cells (ED50s = 8.5 and 4 μM, respectively) and multiple human leukemia cell lines (IC50s = 1.7-5.8 μM).

Product information

CAS Number: 5116-24-5

Molecular Weight: 258.23

Formula: C10H14N2O6

Synonym:

Hydroxymethyldeoxyuridine

α-Hydroxythymidine

2'-Deoxy-5-(hydroxymethyl)uridine

Chemical Name: Uridine, 2'-deoxy-5-(hydroxymethyl)

Smiles: O[C@@H]1C[C@H](O[C@H]1CO)N1C=C(CO)C(=O)NC1=O

InChiKey: IPAVKOYJGUMINP-CSMHCCOUSA-N

InChi: InChI=1S/C10H14N2O6/c13-3-5-2-12(10(17)11-9(5)16)8-1-6(15)7(4-14)18-8/h2,6-8,13-15H,1,3-4H2,(H,11,16,17)/t6-,7+,8+/m1/s1

Technical Data

Appearance: Solid Power.

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥360 days if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined.

HS Tariff Code: 382200

Products are for research use only. Not for human use.