Brexpiprazole


Catalog No. Size PriceQuantity
M9431-2 Solid 2 mg $75
M9431-10 Solid 10 mg $225

Description

Brexpiprazole, also known as OPC-34712, is a novel D2 dopamine partial agonist called serotonin-dopamine activity modulator (SDAM) approved for the treatment of schizophrenia, and as an adjunctive treatment for depression. Although it failed Phase II clinical trials for ADHD, it has been designed to provide improved efficacy and tolerability (e.g., less akathisia, restlessness and/or insomnia) over established adjunctive treatments for major depressive disorder (MDD). Brexpiprazole was approved on 7/10/2015 to treat schizophrenia and as an add on to an antidepressant to treat major depressive disorder

Product information

CAS Number: 913611-97-9

Molecular Weight: 433.57

Formula: C25H27N3O2S

Synonym:

OPC 34712

OPC34712

OPC-34712

Chemical Name: 7-{4-[4-(1-benzothiophen-4-yl)piperazin-1-yl]butoxy}-1,2-dihydroquinolin-2-one

Smiles: O=C1C=CC2=CC=C(C=C2N1)OCCCCN1CCN(CC1)C1C=CC=C2SC=CC=12

InChiKey: ZKIAIYBUSXZPLP-UHFFFAOYSA-N

InChi: InChI=1S/C25H27N3O2S/c29-25-9-7-19-6-8-20(18-22(19)26-25)30-16-2-1-11-27-12-14-28(15-13-27)23-4-3-5-24-21(23)10-17-31-24/h3-10,17-18H,1-2,11-16H2,(H,26,29)

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.

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