Lisinopril

Lisinopril is a drug of the angiotensin-converting enzyme (ACE) inhibitor class used primarily in treatment of high blood pressure, heart failure, and after heart attacks. It is also used for preventing kidney and eye complications in people with diabetes. Its indications, contraindications, and side effects are as those for all ACE inhibitors. A number of properties distinguish it from other ACE inhibitors: It is hydrophilic, has a long half-life and tissue penetration, and is not metabolized by the liver.

Product information

CAS Number: 76547-98-3

Molecular Weight: 405.49

Formula: C21H31N3O5

Synonym:

Prinivil

Zestril

Chemical Name: (2S)-1-[(2S)-6-amino-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}hexanoyl]pyrrolidine-2-carboxylic acid

Smiles: NCCCC[C@H](N[C@@H](CCC1C=CC=CC=1)C(O)=O)C(=O)N1CCC[C@H]1C(O)=O

InChiKey: RLAWWYSOJDYHDC-BZSNNMDCSA-N

InChi: InChI=1S/C21H31N3O5/c22-13-5-4-9-16(19(25)24-14-6-10-18(24)21(28)29)23-17(20(26)27)12-11-15-7-2-1-3-8-15/h1-3,7-8,16-18,23H,4-6,9-14,22H2,(H,26,27)(H,28,29)/t16-,17-,18-/m0/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: Soluble in DMSO

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Akintunde JK, Bolarin OE, Akintunde DG. Garlic capsule and selenium-vitaminsACE combination therapy modulate key antioxidant proteins and cellular adenosine triphosphate in lisinopril-induced lung damage in rats. Drug Metabol Personal Ther. 2016 Mar 1;31(1):47-54.
2. Simonyi G, Ferenci T. [Ramipril plus amlodipine and lisinopril plus amlodipine fixed dose combinations and patient's adherence]. Orv Hetil. 2016 Jan 3;157(1):30-4.

Products are for research use only. Not for human use.