Dalfopristin

Dalfopristin (RP54476) is a semi-synthetic analogue of ostreogyrcin A. Quinupristin/dalfopristin (Q/D) is a parental streptogramin with a spectrum of activity that includes Gram-positive pathogens, including those resistant to other classes of antimicrobial compounds.

Product information

CAS Number: 112362-50-2

Molecular Weight: 690.85

Formula: C34H50N4O9S

Synonym:

RP54476

Chemical Name: (12Z,32S,33R,6R,7R,8E,13E,15E,17S)-33-((2-(diethylamino)ethyl)sulfonyl)-17-hydroxy-6-isopropyl-7,15-dimethyl-5-oxa-11-aza-1(4,2)-oxazola-3(1,2)-pyrrolidinacycloicosaphane-8,13,15-triene-2,4,10,19-tetraone

Smiles: CC1C=CCNC(=O)C=C[C@@H](C)[C@H](OC(=O)[C@H]2[C@@H](CCN2C(=O)C2=COC(CC(=O)C[C@H](O)C=1)=N2)S(=O)(=O)CCN(CC)CC)C(C)C |c:34,t:2,8|

InChiKey: SUYRLXYYZQTJHF-SSBZBSMWSA-N

InChi: InChI=1S/C34H50N4O9S/c1-7-37(8-2)16-17-48(44,45)28-13-15-38-31(28)34(43)47-32(22(3)4)24(6)11-12-29(41)35-14-9-10-23(5)18-25(39)19-26(40)20-30-36-27(21-46-30)33(38)42/h9-12,18,21-22,24-25,28,31-32,39H,7-8,13-17,19-20H2,1-6H3,(H,35,41)/b10-9-,12-11-,23-18-/t24-,25-,28-,31-,32-/m1/s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO 100 mg/mL (144.75 mM) Ethanol 100 mg/mL (144.75 mM)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

References:

1. Joseph M Blondeau, Stephen E Sanche. Expert Opin Pharmac

Products are for research use only. Not for human use.