Apoptosis is a complex series of protease pathways designed to kill cells in a selective manner. Apoptosis can simplistically be defined into linear pathways; however, each pathway is subject to fine control of its activity at multiple points. Other forms of cell survival regulation such as autophagy can impact on the outcome of a primary apoptosis signal. Alternatively, autophagy can be a primary signal that feeds into apoptosis resulting in cell killing. Thus, despite many years of investigation, there still remain many unanswered questions in the regulation of cell survival by apoptosis.
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Zibotentan (ZD4054)
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ZLDI-8
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ZM 336372
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ZM-447439
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Zoledronic Acid
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Zoledronic Acid, (hydrate)
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α-Lipoic Acid
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α-Thujone
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β-Carotene
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β-Elemonic acid
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β-Ionone
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ζ-Stat trisodium
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