PDM2 - CAS# 688348-25-6


Catalog No. Size PriceQuantity
M16240-C Contact sales@xcessbio.com for quotation $100

Description

PDM2 is a selective, high-affinity aryl hydrocarbon receptor (AhR) antagonist with an Ki of 1.2±0.4 nM.

Product information

CAS Number: 688348-25-6

Molecular Weight: 283.58

Formula: C14H9Cl3

Chemical Name: 1,3-dichloro-5-[(E)-2-(4-chlorophenyl)ethenyl]benzene

Smiles: ClC1C=CC(/C=C/C2C=C(Cl)C=C(Cl)C=2)=CC=1

InChiKey: JMYNPQVCVQVODQ-OWOJBTEDSA-N

InChi: InChI=1S/C14H9Cl3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h1-9H/b2-1+

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 50 mg/mL (176.32 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

PDM2 (Compound 4b) exhibits a Ki of 1.2±0.4 nM for AhR and no affinity for estrogen receptor (ER), confirming that replacement of hydroxyl with chloride abolished binding on ER and increased dramatically the affinity for AhR.

Products are for research use only. Not for human use.

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