Description
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research.
Product information
CAS Number: 38274-54-3
Molecular Weight: 228.63
Formula: C9H9ClN2O3
Chemical Name: 2-[(4-chlorophenyl)formamido]-N-hydroxyacetamide
Smiles: ONC(=O)CNC(=O)C1=CC=C(Cl)C=C1
InChiKey: JFZGBMJPJZDNNT-UHFFFAOYSA-N
InChi: InChI=1S/C9H9ClN2O3/c10-7-3-1-6(2-4-7)9(14)11-5-8(13)12-15/h1-4,15H,5H2,(H,11,14)(H,12,13)
Technical Data
Appearance: Solid Power
Purity: ≥98% (or refer to the Certificate of Analysis)
Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis
Storage Condition: Dry, dark and -20 oC for 1 year or refer to the Certificate of Analysis.
Shelf Life: ≥12 months if stored properly.
Stock Solution Storage: 0 - 4 oC for 1 month or refer to the Certificate of Analysis.
Drug Formulation: To be determined
HS Tariff Code: 382200
How to use
In Vivo:
Benurestat administration, 25 mg/kg, 50 mg/kg, or 100 mg/kg, causes a decrease in the urinary excretion of ammonia from rats with experimental P. mirabilis genitourinary tract infection. The number of viable bacteria present in the bladders of infected rats is significantly less after the administration of Benurestat plus Nitrofurantoin, Sulfamethoxazole, or Ampicillin than the respective numbers that are obtained from control infected rats or from rats administered either component of the combination separately.
Products are for research use only. Not for human use.
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