Bacitracin (Zinc)

Bacitracin Zinc is a cyclic polypeptide antibiotic. Formulations containing bacitracin, often combined with other antibiotics, are used for topical treatment of infections in humans and animals. The activity of bacitracin can be enhanced by zinc. Bacitracin sequesters C55-isopropyl pyrophosphate (IPP), a lipid carrier in peptidoglycan synthesis, and in this way disrupts cell wall biosynthesis.

Product information

CAS Number: 1405-89-6

Molecular Weight: 1486.09

Formula: C66H101N17O16SZn

Synonym:

Bacitracin zinc salt

Zinc bacitracin

Chemical Name: zinc(2+) (4R)-4-[(2S)-2-{[2-(1-amino-2-methylbutyl)-4, 5-dihydro-1, 3-thiazol-4-yl]formamido}-4-methylpentanamido]-4-{[(1S, 2S)-1-{[(3S, 6R, 9R, 12R, 15R, 18R, 21S)-18-(3-aminopropyl)-12-benzyl-15-[(2R)-butan-2-yl]-3-(carbamoylmethyl)-6-(carboxylatomethyl)-9-[(1H-imidazol-5-yl)methyl]-2, 5, 8, 11, 14, 17, 20-heptaoxo-1, 4, 7, 10, 13, 16, 19-heptaazacyclopentacosan-21-yl]carbamoyl}-2-methylbutyl]carbamoyl}butanoate

Smiles: [Zn+2].CC(C)C[C@H](NC(=O)C1CSC(=N1)C(N)C(C)CC)C(=O)N[C@H](CCC([O-])=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CCCCNC(=O)[C@H](CC(N)=O)NC(=O)[C@@H](CC([O-])=O)NC(=O)[C@@H](CC2=CN=CN2)NC(=O)[C@@H](CC2=CC=CC=C2)NC(=O)[C@H](NC(=O)[C@@H](CCCN)NC1=O)[C@H](C)CC

InChiKey: UCRLQOPRDMGYOA-BWBYNRQYSA-L

InChi: InChI=1S/C66H103N17O16S.Zn/c1-9-35(6)52(69)66-81-48(32-100-66)63(97)76-43(26-34(4)5)59(93)74-42(22-23-50(85)86)58(92)83-53(36(7)10-2)64(98)75-40-20-15-16-25-71-55(89)46(29-49(68)84)78-62(96)47(30-51(87)88)79-61(95)45(28-39-31-70-33-72-39)77-60(94)44(27-38-18-13-12-14-19-38)80-65(99)54(37(8)11-3)82-57(91)41(21-17-24-67)73-56(40)90;/h12-14,18-19,31,33-37,40-48,52-54H,9-11,15-17,20-30,32,67,69H2,1-8H3,(H2,68,84)(H,70,72)(H,71,89)(H,73,90)(H,74,93)(H,75,98)(H,76,97)(H,77,94)(H,78,96)(H,79,95)(H,80,99)(H,82,91)(H,83,92)(H,85,86)(H,87,88);/q;+2/p-2/t35?,36-,37+,40-,41+,42+,43-,44+,45+,46-,47+,48?,52?,53-,54+;/m0./s1

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

Products are for research use only. Not for human use.